Revolutionary exosome therapy to regenerate, repair and restore your skin at the cellular level.
Exosome for Skin Treatments
Beyond Botox and Fillers: The Future of Skin Rejuvenation is Here
Loss of elasticity, skin relaxation, wrinkles and a rough appearance are typical signs of skin aging. How to fight it? Traditional treatments like Botox, fillers, and even PRP only provide temporary relief, masking symptoms without addressing the root causes.
ExoSkin – The New Era of Regenerative Skin Therapy
With ExoSkin therapy, exosomes can boost the skin’s natural healing process, especially when delivered deeply into the dermis. The skin will be able to rebuild itself in a natural, healthy way from the inside out. ExoSkin, the new frontier of exosome skin rejuvenation, can increase skin collagen in the treated areas by up to six-fold and increases elastin levels by up to 300%.
600% increase in collagen production
300% increase in elastin levels
Natural cellular regeneration
Long-lasting results
Stem cells act as real collagen and elastin factories, eliminating the limits of botox and fillers by addressing the root causes of skin aging, not just masking its symptoms.
ExoSkin Therapy: Four Specialized Treatment Areas
ExoSkin harnesses the power of adipose-derived mesenchymal stem cell (AD-MSC) exosomes to target specific skin concerns through their regenerative, anti-inflammatory, and angiogenic properties. Our comprehensive approach addresses four key areas of aesthetic medicine:
SKIN AGING
Combat the visible signs of aging through cellular regeneration. AD-MSC exosomes stimulate cell proliferation, collagen synthesis, and ECM remodeling while providing antioxidant protection to restore skin’s youthful appearance, texture, and firmness.
WRINKLES
Smooth away fine lines and deep wrinkles naturally. Exosomes promote collagen synthesis, cell proliferation, and ECM remodeling to improve skin elasticity and firmness. When combined with autologous fat transfer, results are even more dramatic and long-lasting.
HEAD AND NECK AGING
Address complex aging in delicate areas. Exosomes promote skin rejuvenation, soft tissue volume restoration, and improved blood supply to the neck and facial regions. Perfect for patients seeking non-surgical solutions to age-related changes in these sensitive areas.
SCARS AND STRETCH MARKS
Repair damaged skin tissue effectively. Exosomes regulate collagen synthesis and remodeling, promote cell proliferation, and reduce inflammation. Ideal for hypertrophic, keloid, and atrophic scars, as well as stretch marks from pregnancy or weight changes.
Advantages of Exosome Therapy
AD-MSC exosomes work through multiple biological mechanisms to reverse the signs of aging and repair damaged tissue at the cellular level. Here are the key ways they contribute to skin rejuvenation and regeneration:
Cell Proliferation and Migration
AD-MSC exosomes contain various growth factors, cytokines, and signaling molecules that stimulate the proliferation and migration of skin cells, such as fibroblasts and keratinocytes. This helps improve skin thickness, texture, and overall appearance.
Collagen Synthesis
AD-MSC exosomes can promote collagen synthesis in fibroblasts by transferring bioactive molecules like transforming growth factor-beta (TGF-β) and connective tissue growth factor (CTGF). Increased collagen production can help improve skin elasticity, firmness, and texture, reducing the appearance of wrinkles and fine lines.
Extracellular Matrix (ECM) Remodeling
AD-MSC exosomes can regulate the synthesis and degradation of extracellular matrix proteins, such as collagen, elastin, and hyaluronic acid, which are essential for maintaining skin structure and hydration. This helps restore the skin’s natural support structure and improve its appearance.
Angiogenesis
Exosomes can promote blood vessel formation by transferring pro-angiogenic factors, such as vascular endothelial growth factor (VEGF), to endothelial cells. Improved blood supply can enhance the delivery of oxygen and nutrients to the skin, promoting healing and rejuvenation.
Immunomodulation
AD-MSC exosomes can modulate the immune response, suppressing inflammation and promoting tissue repair. By reducing inflammation, they can help minimize potential side effects and complications associated with skin rejuvenation treatments.
Antioxidant Effects
Exosomes can protect skin cells from oxidative stress and damage by transferring antioxidant molecules, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx). This can help maintain skin health and reduce the signs of aging.
Overall, adipose-derived mesenchymal stem cell exosomes can contribute to skin rejuvenation and repair through various mechanisms, making them a promising approach for treating multiple skin concerns.
Mode of Action: How Exosomes Work at the Cellular Level
Exosomes derived from mesenchymal stem cells (MSCs) have been studied as a potential therapeutic option for improving skin health. The mode of action of MSC-derived exosomes involves several sophisticated mechanisms:
Ideal Candidates for EXOSKIN Treatment
Mesenchymal stem cell (MSC)-derived exosomes have shown potential in addressing various skin concerns due to their regenerative, anti-inflammatory, and angiogenic properties. Ideal patients for MSC-derived exosome treatment may include those who:
Seek Non-Surgical Options
Patients looking for non-surgical alternatives to address signs of aging, wrinkles, fine lines, scars, or other skin concerns may benefit from MSC-derived exosome treatment. This innovative therapy offers effective results without the need for invasive procedures, making it ideal for those seeking minimally invasive solutions.
Experience Age-Related Skin Changes
Patients with reduced skin elasticity, collagen degradation, loss of volume, or other age-related changes may find MSC-derived exosome treatment helpful in promoting regeneration and protecting cells from oxidative stress. The treatment helps restore skin’s youthful appearance naturally.
Desire a More Natural Approach
Patients seeking a more natural treatment option may find MSC-derived exosome treatment suitable, as it harnesses the body’s own regenerative capabilities without synthetic materials. This biocompatible approach works with your body’s natural healing processes.
Have Sensitive Skin or Allergies
Patients with sensitive skin or allergies to certain components in synthetic fillers or other treatments may find MSC-derived exosome treatment more biocompatible and less likely to cause adverse reactions. The natural origin of exosomes reduces the risk of allergic responses.
Look for a Complementary Therapy
Patients who are already receiving other skin treatments, such as laser therapy, microneedling, or chemical peels, may benefit from MSC-derived exosome treatment as a complementary therapy to enhance overall results. Exosomes can amplify the effectiveness of other aesthetic procedures.
Are in Overall Good Health
Patients should be in good general health, with no active infections, uncontrolled medical conditions, or contraindications to treatment. Good health increases the likelihood of successful treatment and reduces potential risks and complications.
It’s important to note that while MSC-derived exosome treatment may be suitable for many patients, the decision should be made on an individual basis after thorough evaluation and consultation with a qualified medical professional. They can assess the patient’s specific needs, skin condition, and medical history to determine the most appropriate treatment approach.
The EXOSKIN Procedure: Science Meets Safety
Exosomes are extracted from human mesenchymal stem cells and thoroughly tested for quality and quantity. Containing valuable lipids, messenger RNA, cytokines, and proteins, our bank of Exosomes will be administered according to the Specialist’s recommendation.
With its specialized laboratories housing all the equipment needed to carry out any Exosome treatment successfully, Bioscience Institute is the only clinic with the ability to help patients achieve the desired results. Before any procedure, extensive steps are taken to ensure that all products undergo a strict screening process that certifies sterility, safety for use, and endotoxin testing.
Depending on the specific treatment area and patient needs, exosomes can be delivered through various methods including microinjection, mesotherapy, cannula injection, or combined approaches for optimal results.
In-depth Information
Would you like to explore further or learn more? Access comprehensive explanations by expanding the sections below.
What are Exosomes and How Do They Work?
What are Exosomes and How Do They Work?
Exosomes are tiny extracellular vesicles secreted by mesenchymal stem cells (MSCs) that carry bioactive molecules such as proteins, lipids, messenger RNA, and cytokines. These vesicles act as biological messengers, delivering regenerative signals directly to target cells.
Unlike stem cell therapy, which relies on the transplanted cells to integrate into tissues, exosome therapy harnesses the natural communication system of stem cells without introducing living cells into the body. This makes the treatment safer, easier to administer, and less likely to provoke immune reactions.
Exosomes work by:
• Stimulating tissue repair and cellular regeneration
• Reducing inflammation and oxidative stress
• Promoting collagen and elastin production
• Enhancing blood vessel formation (angiogenesis)
• Modulating immune responses
Their small size allows them to penetrate deep into the skin layers, delivering therapeutic effects at the cellular level for comprehensive rejuvenation.
Exosomes vs. Traditional Stem Cell Therapy
Exosomes vs. Traditional Stem Cell Therapy
While both exosomes and stem cells originate from the same source—mesenchymal stem cells—they represent different therapeutic approaches with distinct advantages.
Traditional Stem Cell Therapy:
• Uses living cells that must survive, integrate, and differentiate in the recipient tissue
• Requires careful handling and storage
• May trigger immune responses in some cases
• More complex administration process
Exosome Therapy:
• Uses cell-free bioactive vesicles that deliver regenerative signals
• More stable and easier to store
• Lower risk of immune rejection
• Can be administered through multiple methods (injection, topical, etc.)
• Immediate action—no need for cell engraftment
Both approaches promote regeneration, but exosomes offer a more targeted, versatile, and accessible solution for skin rejuvenation. At Bioscience Institute, we utilize expanded MSC-derived exosomes for maximum potency and consistency.
