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XHAIR

Exosomes cosmetics for hair loss

Regenerative Exosome Therapy for Hair Loss

The adipose-derived mesenchymal stem cell (ADMSC) exosomes have demonstrated potential in promoting hair growth and improving hair health. Cosmetics containing ADMSC exosomes could harness their regenerative and immunomodulatory properties to address hair loss and keep the scalp balanced.

ADMSC exosome-based actives are the key ingredient in XHAIR for the treatment of hair loss, providing the following targeted benefits:

  • Promotion of hair growth: XHAIR may stimulate the activation and proliferation of hair follicle stem cells, initiate the anagen phase of the hair cycle, and support new strands.
  • Improved hair health: Each application delivers proteins, growth factors, and microRNAs that influence cell proliferation, differentiation, and survival.
  • Scalp health: Immunomodulatory properties help regulate local immune responses, reducing inflammation and creating a favorable environment for hair growth.
  • Nourishment and protection: The formula supplies essential nutrients, growth factors, and signaling molecules to nourish follicles and protect them from stress.

For best results we also recommend the XPREP Hair Follicle Purification Cycle Shampoo, specifically formulated to prepare and clean the scalp before every XHAIR session.

Key Bioactive Complexes

XHAIR combines five complementary bioactive complexes so every scalp receives immediate support and long-term regeneration:

  • Malus Domestica Fruit Cell Culture Extract safeguards follicular stem cells and prolongs the anagen phase.
  • Caffeine energizes follicles, helps counter DHT, and improves microcirculation.
  • Adenosine boosts dermal papilla activity, optimizes growth factor expression, and keeps the anagen phase active.
  • Multi-Active Nutrient Complex of ginseng, amino acids, vitamins, and minerals reinforces fiber strength, calms inflammation, and feeds follicles.
  • Lysophosphatidic Acid (LPA) activates dedicated receptors to stimulate cell proliferation and sustain the growth cycle.

Mode of Action of XHAIR Ingredients

Expand each active below to understand how it supports the scalp.

Malus Domestica Fruit Cell Culture Extract

Malus Domestica Fruit Cell Culture Extract, derived from the heritage Uttwiler Spaetlauber apple variety, is a plant-based ingredient with potential benefits for hair growth and hair loss prevention. Although research on its specific mode of action is limited, the extract contains plant stem cells and protective compounds that support scalp vitality.

Its proposed modes of action include:

  1. Prolonging the anagen phase: Helps hair follicles remain in their active growth stage longer.
  2. Protection against oxidative stress: Provides antioxidants that shield follicles from free radical damage.
  3. Activation of hair follicle stem cells: Stimulates follicular stem cells to encourage regeneration.
  4. Anti-inflammatory effects: Calms irritation on the scalp that could otherwise disrupt growth.

By preserving the well-being of follicular stem cells, this extract keeps the growth cycle more stable over time.

Caffeine

Caffeine supports the scalp through several evidence-backed pathways:

  1. Stimulating hair growth: Extends the anagen phase and encourages keratinocyte proliferation.
  2. Blocking DHT: Helps inhibit 5-alpha-reductase to limit the impact of dihydrotestosterone.
  3. Improving blood circulation: Boosts microcirculation so follicles receive oxygen and nutrients.

These mechanisms make caffeine a reliable booster for both male and female thinning patterns.

Adenosine

Adenosine is a naturally occurring nucleoside that supports follicular metabolism and signaling:

  1. Prolonging the anagen phase: Keeps follicles in growth mode for longer periods.
  2. Stimulating hair follicle activity: Activates dermal papilla cells and encourages the formation of new follicles.
  3. Enhancing blood flow: Acts as a vasodilator to improve oxygen and nutrient delivery.
  4. Regulating hair growth factors: Influences FGF-7 and VEGF expression to sustain follicle development.
  5. Inhibiting DHT: Helps counter the hormonal cascade associated with pattern hair loss.

Consistent topical use of adenosine has been linked to visible density gains in clinical observations.

Multi-Active Nutrient Complex

The combination of Panax ginseng root extract, hydrolyzed soy protein, dimethicone copolyol, acetyl tyrosine, arginine, arctium majus root extract, zinc gluconate, polyquaternium-11, calcium pantothenate, citrulline, glucosamine HCl, ornithine HCl, niacinamide, and biotin provides multi-target support for hair density.

  1. Panax ginseng root extract: Stimulates circulation and delivers essential nutrients to follicles.
  2. Hydrolyzed soy protein: Strengthens and moisturizes hair fibers to limit breakage.
  3. Dimethicone copolyol: Creates a protective film that reduces mechanical damage.
  4. Acetyl tyrosine, arginine, citrulline, ornithine HCl: Supply amino acids that fuel keratin production.
  5. Arctium majus root extract: Offers anti-inflammatory and antioxidant benefits for a healthy scalp.
  6. Zinc gluconate: Addresses deficiencies linked to shedding and supports follicle function.
  7. Polyquaternium-11: Conditions the fiber for improved manageability.
  8. Calcium pantothenate (vitamin B5): Improves strength and thickness.
  9. Glucosamine HCl: Delivers structural nutrients to the follicle matrix.
  10. Niacinamide (vitamin B3): Enhances microcirculation to improve nutrient delivery.
  11. Biotin (vitamin B7): Reinforces keratin structure for resilient strands.

Together they create a comprehensive nutrient base that protects fibers, soothes the scalp, and sustains healthy growth.

Lysophosphatidic Acid (LPA)

Lysophosphatidic Acid (LPA) is a bioactive lipid that influences cell proliferation, differentiation, and migration.

  1. Activation of LPA receptors: Binds to LPARs on hair follicle cells to stimulate proliferation.
  2. Prolonging the anagen phase: Encourages follicles to remain in the growth cycle by limiting apoptosis.
  3. Regulation of hair follicle stem cells: Supports the regenerative behavior required for continuous hair formation.

These actions make LPA a strategic messenger inside XHAIR to keep follicles productive.

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